| 1 | Lionel Messi
FC Barcelona | FC Barcelona | 33 | 25 |
| 2 | Karim Benzema
Real Madrid | Real Madrid | 37 | 21 |
| 3 | Gerard Moreno
Villarreal CF | Villarreal CF | 35 | 18 |
| 4 | Luis Suárez
FC Barcelona | FC Barcelona | 28 | 16 |
| 5 | Raúl García
Athletic Bilbao | Athletic Bilbao | 35 | 15 |
| 6 | Lucas Ocampos
Sevilla FC | Sevilla FC | 33 | 14 |
| - | Iago Aspas
Celta de Vigo | Celta de Vigo | 37 | 14 |
| 8 | Ante Budimir
RCD Mallorca | RCD Mallorca | 35 | 13 |
| 9 | Alvaro Morata
Atlético Madrid | Atlético Madrid | 34 | 12 |
| 10 | Willian José
Real Sociedad | Real Sociedad | 37 | 11 |
| - | Roger Martí Salvador
Levante UD | Levante UD | 36 | 11 |
| - | Santi Cazorla
Villarreal CF | Villarreal CF | 35 | 11 |
| - | Lucas
Alavés | Alavés | 34 | 11 |
| - | Jaime Mata
Getafe CF | Getafe CF | 34 | 11 |
| - | Joselu Sanmartín
Alavés | Alavés | 36 | 11 |
| - | Sergio Ramos
Real Madrid | Real Madrid | 35 | 11 |
| 17 | Ángel
Getafe CF | Getafe CF | 32 | 10 |
| - | Loren Morón
Real Betis | Real Betis | 36 | 10 |
| - | Maximiliano Gomez Gonzalez
Valencia CF | Valencia CF | 33 | 10 |
| - | Carlos Fernandez Luna
Granada CF | Granada CF | 34 | 10 |
| - | Mikel Oiarzabal
Real Sociedad | Real Sociedad | 37 | 10 |
| 22 | Alexander Isak
Real Sociedad | Real Sociedad | 37 | 9 |
| - | Luis Avila
Osasuna | Osasuna | 20 | 9 |
| - | Óscar Arnaiz
Leganés | Leganés | 30 | 9 |
| - | Antoine Griezmann
FC Barcelona | FC Barcelona | 35 | 9 |
| 26 | Arturo Vidal
FC Barcelona | FC Barcelona | 33 | 8 |
| - | Joaquín
Real Betis | Real Betis | 34 | 8 |
| - | Dawin Machis
Granada CF | Granada CF | 36 | 8 |
| - | Borja Mayoral
Levante UD | Levante UD | 34 | 8 |
| - | Youssef En-Nesyri
Sevilla FC | Sevilla FC | 18 | 8 |
| - | Ruben Garcia Santos
Osasuna | Osasuna | 30 | 8 |
| - | Fabian Orellana
Eibar | Eibar | 29 | 8 |
| - | Sergio Guardiola Navarro
Real Valladolid | Real Valladolid | 35 | 8 |
| - | Daniel Parejo
Valencia CF | Valencia CF | 35 | 8 |
| 35 | Ansu Fati
FC Barcelona | FC Barcelona | 24 | 7 |
| - | Enis Bardhi
Levante UD | Levante UD | 30 | 7 |
| - | Martin Braithwaite
FC Barcelona | FC Barcelona | 11 | 7 |
| - | Roberto Soldado
Granada CF | Granada CF | 33 | 7 |
| - | Portu
Real Sociedad | Real Sociedad | 35 | 7 |
| - | Antonio Puertas
Granada CF | Granada CF | 36 | 7 |
| - | Nabil Fekir
Real Betis | Real Betis | 32 | 7 |
| - | Roberto Torres
Osasuna | Osasuna | 36 | 7 |
| 43 | Karl Toko Ekambi
Villarreal CF | Villarreal CF | 18 | 6 |
| - | Charles
Eibar | Eibar | 30 | 6 |
| - | Kevin Gameiro
Valencia CF | Valencia CF | 29 | 6 |
| - | João Félix
Atlético Madrid | Atlético Madrid | 27 | 6 |
| - | Santiago Mina Lorenzo
Celta de Vigo | Celta de Vigo | 34 | 6 |
| - | Luuk de Jong
Sevilla FC | Sevilla FC | 35 | 6 |
| - | Enes Ünal
Real Valladolid | Real Valladolid | 35 | 6 |
| - | Iñaki Williams
Athletic Bilbao | Athletic Bilbao | 38 | 6 |